Curated Optogenetic Publication Database

Search precisely and efficiently by using the advantage of the hand-assigned publication tags that allow you to search for papers involving a specific trait, e.g. a particular optogenetic switch or a host organism.

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1.

Temporal induction of Lhx8 by optogenetic control system for efficient bone regeneration.

blue FKF1/GI HeLa mouse in vivo primary rat BMSCs Cell differentiation
Stem Cell Res Ther, 10 Jun 2021 DOI: 10.1186/s13287-021-02412-8 Link to full text
Abstract: The spatiotemporal regulation of essential genes is crucial for controlling the growth and differentiation of cells in a precise manner during regeneration. Recently, optogenetics was considered as a potent technology for sophisticated regulation of target genes, which might be a promising tool for regenerative medicine. In this study, we used an optogenetic control system to precisely regulate the expression of Lhx8 to promote efficient bone regeneration.
2.

Optogenetic gene editing in regional skin.

blue CRY2/CIB1 mouse epidermal keratinocytes mouse in vivo
Cell Res, 31 Jul 2019 DOI: 10.1038/s41422-019-0209-9 Link to full text
Abstract: Abstract not available.
3.

An extraordinary stringent and sensitive light-switchable gene expression system for bacterial cells.

blue VVD YtvA E. coli Control of cytoskeleton / cell motility / cell shape Transgene expression Cell death
Cell Res, 17 Jun 2016 DOI: 10.1038/cr.2016.74 Link to full text
Abstract: Light-switchable gene expression systems provide transient, non-invasive and reversible means to control biological processes with high tunability and spatiotemporal resolution. In bacterial cells, a few light-regulated gene expression systems based on photoreceptors and two-component regulatory systems (TCSs) have been reported, which respond to blue, green or red light.
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